In the period 1987 to 1989 a stream water sampling and analysis program for the southern Cayuga Lake basin was carried out as a part of the continuing analysis of central NY water quality (Manuscripts and Water Quality Data for Watersheds and Lakes in Central NY, 1972-2003, online: http://hdl.handle.net/1813/2547; Water quality data for Fall Creek (Tompkins County, NY) sampling sites: 1972-1995, online: http://hdl.handle.net/1813/8148; Water quality data for well, stream, and seep samples from the Harford Teaching and Research Farm (Cortland County, NY): 1974-1994, online: http://hdl.handle.net/1813/8351; Water quality data for Kashong Creek Watershed (Ontario County and Yates County, NY) sampling sites: 1977-1979, online: http://hdl.handle.net/1813/8380). The samples were analyzed for suspended solids, NO3-N, and total dissolved phosphorus. The streams sampled were Fall Creek, Six Mile Creek, Cascadilla Creek and Inlet. Samples included all seasons and all flow regimes. On average, the NO3-N concentration in Fall Creek was 1.26 ppm, about twice that in the other streams. In the period 1972-1975, average NO3-N concentration was 0.97. The suspended solids in Six Mile Creek at Burns Road was higher than that in the other streams but at a location near its confluence with the lake (after passing though 2 impoundments), the concentration was comparable. Total dissolved P was lowest for inlet. In other locations (Six Mile Creek and Cascadilla) the TDP tended to increase after passage though City of Ithaca. A comparison of the suspended solids load in Fall Creek, 1973-1974 with 1987-1989 showed no important difference.